Author

Ampon Sae Her

University of California, Los AngelesORCID 0000-0001-9594-8678Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Approach:experimental assay· 1

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Tamir GoneniD· 1 shared Xuelang MuiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperMolecular Biology

Tamir GonenORCID

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Molecular BiologybioRxivPreprintOct 24, 2025

pH-dependent regulation in SLC38A9

Xuelang Mu, Ampon Sae Her, Tamir Gonen

This study shows that SLC38A9, a lysosomal amino acid transporter, has pH-dependent arginine uptake regulated by the histidine residue His544, which influences transport through protonation/deprotonation rather than direct substrate binding.

DOI 10.1101/2025.10.24.684471

experimental assay

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