Author

Zahava Siegfried

Hebrew University of JerusalemORCID 0000-0001-9649-7434Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Rotem KarniiD· 2 shared Adina R. HeinbergiD· 1 shared Anurag Prabhu· 1 shared Anurag V PrabhuiD· 1 shared Carla Azar-Koussa· 1 shared Efraim RahamimiD· 1 shared Ela Elyada· 1 shared Eran ZimraniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Rotem KarniORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 7, 2026

Targeting the 3' splice site by a decoy oligonucleotide attenuates U2AF1 splicing activity and inhibits leukemia

Carla Azar-Koussa, Marina Sakran, Efraim Rahamim…·Rotem Karni

This paper develops an RNA decoy strategy to inhibit splicing factor activity in leukemia, showing it reduces tumor burden in vivo regardless of spliceosomal mutations.

DOI 10.64898/2026.06.30.735457

humanmultiome

𝕏 PostBluesky

GeneticsbioRxivPreprintMar 18, 2026

Molecular characterization of the heterozygous loss of function mutations in the X-linked PCDH19 gene causing PCDH19-Cluster Epilepsy

Shivang Khandelwal, Ela Elyada, Reut Japha…·Rotem Karni

The paper investigates PCDH19-Cluster Epilepsy by generating mouse and human models, identifying differentially expressed genes and morphological changes linked to PCDH19 mutations.

DOI 10.64898/2026.03.16.712128

mousehuman

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