Author

Reza Rezaei

University of Pennsylvania;ORCID 0000-0001-9652-9328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Alexander A Shestov· 1 shared Bakir Valentic· 1 shared Carl H. JuneiD· 1 shared Darsh Vithlani· 1 shared Farzin RoohvandiD· 1 shared Jordan Reff· 1 shared Kayhan AzadmaneshiD· 1 shared Kush Parikh· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Alexander A Shestov

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Author profile →

2 papers

Recent·Most cited

Receptor-guided engineering of oncolytic vaccinia creates a synthetic support niche for off-the-shelf NK cell therapy

Reza Rezaei, Zhiyang Gan, Ngomu Akeem Akilimali, Jordan Reff, Meiyin Lin, Yansen Xiao, Kush Parikh, Darsh Vithlani, Bakir Valentic, Alexander A Shestov, Ugur Uslu, Taha Azad, Roddy S OConnor, Carl H. June, Neil C. Sheppard

This paper develops a framework to engineer oncolytic vaccinia virus to support off-the-shelf NK cells by aligning viral payloads with NK cell manufacturing limitations.

bioRxiv · Nov 9, 2026 · PreprintBioengineering

Optimizing Consensus Generation Algorithms for Highly Variable Amino Acid Sequence Clusters

Reyhaneh Mohabati, Reza Rezaei, Nasir Mohajel, Mohammad Mehdi Ranjbar, Kayhan Azadmanesh, Farzin Roohvand

The paper introduces a novel consensus generation algorithm for highly variable amino acid sequences, showing it preserves epitopes and maintains antigenicity compared to existing methods.

bioRxiv · Nov 8, 2020 · PreprintBioinformatics