Author

Simian Cai

Cornell UniversityORCID 0000-0001-9686-0635Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Aixin Shi· 1 shared Alexei Wirganowicz· 1 shared Ali El‐ArmoucheiD· 1 shared Ann Li· 1 shared Chao YiiD· 1 shared Chenzhi Cai· 1 shared Christopher L. AntosiD· 1 shared Dorin ArtziiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Aixin Shi

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Repurposed endogenous virus-like vesicles mediate dendritic cell long-range antigen presentation and T cell activation for enhanced cancer vaccination

Wenchao Gu, Ruoxin Li, Hayleigh Goodrich, Dorin Artzi, Simian Cai, Aixin Shi, Irene Tsai, Guoting Qin, Ann Li, Evelyn Goldwasser, Nadine Elkasri, Sijin Luozhong, Shinji Kamada, Yizhou Wu, Vaibhav Upadhayay, , Shaoyi Jiang

This paper shows that dendritic cells use virus-like vesicles to enhance antigen presentation and T cell activation, leading to improved cancer vaccination.

bioRxiv · Nov 23, 2025 · PreprintBioengineering

A calcineurin-mediated scaling mechanism that controls a K+-leak channel to regulate morphogen and growth factor transcription

Chao Yi, Tim W.G.M. Spitters, Ezz Al-Din Ahmed Al-Far, Sen Wang, TianLong Xiong, Simian Cai, Xin Yan, Kaomei Guan, Michael Wagner, Ali El‐Armouche, Christopher L. Antos

The paper shows how calcineurin regulates Kcnk5b to control gene expression and allometric growth in zebrafish appendages.

bioRxiv · Jul 3, 2020 · PreprintDevelopmental Biology