Author

Frances L. Dearden

University of CambridgeORCID 0000-0001-9729-0187Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne C. Ferguson‐SmithiD· 2 shared Ana Moreno-Barriga· 1 shared Ariella Weinberg‐ShukroniD· 1 shared Carol A. EdwardsiD· 1 shared Lisa C. Hülsmann· 1 shared Lok Ting Nick NewiD· 1 shared Marco Müller· 1 shared Nozomi TakahashiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Anne C. Ferguson‐SmithORCID

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2 papers

Recent·Most cited

GeneticsNature CommunicationsPeer-reviewedSep 2, 2026

Regulatory Mechanisms of Maternal Imprinting at the Dlk1-Dio3 Domain

Ariella Weinberg‐Shukron, Frances L. Dearden, Ana Moreno-Barriga…·Anne C. Ferguson‐Smith

The paper investigates regulatory mechanisms of maternal imprinting at the Dlk1-Dio3 domain, showing that loss of expression is more detrimental than gain and identifying active regulatory factors on the unmethylated maternal chromosome.

DOI 10.1038/s41467-026-77129-4

mouseDNA methylation

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Molecular BiologybioRxivPreprintMar 17, 2021

Subnuclear localisation is associated with gene activation not repression or parental origin at the imprinted Dlk1-Dio3 locus

Rahia Mashoodh A, Lisa C. Hülsmann, Frances L. Dearden…·Anne C. Ferguson‐Smith

The paper investigates the relationship between subnuclear localization and gene expression at the imprinted Dlk1-Dio3 locus, finding that transcriptional activity, not repression or parental origin, determines localization.

DOI 10.1101/2021.03.17.435843

mouseexperimental assay

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