Author

Roderick Adrian Slavcev

University of WaterlooORCID 0000-0001-9738-1978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Rohini Prakash· 2 shared Deborah Pushparajah· 1 shared Jamie Lam· 1 shared Nafiseh NafissiiD· 1 shared Salma Jimenez· 1 shared Shirley Lau WongiD· 1 shared Siddarth ChandrasekaraniD· 1 shared Steven J. HerschiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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2 shared papersMolecular Biology

Rohini Prakash

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A novel miniaturized filamentous phagemid as a gene delivery vehicle to target mammalian cells

Shirley Lau Wong, Salma Jimenez, Deborah Pushparajah, Rohini Prakash, Roderick Adrian Slavcev

This paper develops a novel gene delivery vector based on the M13 phage, showing improved transgene expression through vector minimization and targeting ligand display.

Molecular Therapy — Nucleic Acids · May 19, 2025Peer-reviewedMolecular Biology

An E. coli-based platform for the production and assembly of anellovirus vectors

Rohini Prakash, Roderick Adrian Slavcev

This paper develops an E. coli-based system for producing anellovirus vectors for gene therapy, demonstrating successful expression and assembly of capsid proteins.

bioRxiv · Oct 30, 2024 · PreprintMolecular Biology

Manufacturing DNA in E. coli yields higher fidelity DNA than in vitro enzymatic synthesis

Steven J. Hersch, Siddarth Chandrasekaran, Jamie Lam, Nafiseh Nafissi, Roderick Adrian Slavcev

This study compares DNA fidelity between in vitro enzymatic synthesis and E. coli-produced DNA, finding that E. coli yields significantly fewer mutations.

bioRxiv · Sep 12, 2023 · PreprintSynthetic Biology