Author

Steven J. Hersch

University of CalgaryORCID 0000-0001-6186-0133Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Research Focus:protein design· 1 Approach:statistical model· 1

Frequent Co-Authors

Jamie Lam· 1 shared Linh LamiD· 1 shared Nafiseh NafissiiD· 1 shared Roderick Adrian SlavceviD· 1 shared Siddarth ChandrasekaraniD· 1 shared Tao DongiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperSynthetic Biology

Jamie Lam

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintSep 12, 2023

Manufacturing DNA in E. coli yields higher fidelity DNA than in vitro enzymatic synthesis

Steven J. Hersch, Siddarth Chandrasekaran, Jamie Lam…·Roderick Adrian Slavcev

This study compares DNA fidelity between in vitro enzymatic synthesis and E. coli-produced DNA, finding that E. coli yields significantly fewer mutations.

DOI 10.1101/2023.09.12.557453

E. coliDNA methylation

𝕏 PostBluesky

Molecular BiologymBioPeer-reviewedJul 20, 2021

Engineered type six secretion systems deliver active exogenous effectors and Cre recombinase

Steven J. Hersch, Linh Lam, Tao Dong

The paper develops a method to deliver active Cre recombinase and exogenous effectors using engineered type six secretion systems, enabling genetic editing without DNA introduction.

29 citations

bacteria (other)experimental assay

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