Author

Tim H. Marczylo

UK Health Security AgencyORCID 0000-0001-9744-473XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Emma Quartermain· 1 shared Jinkang Zhang· 1 shared Miriam Naomi JacobsiD· 1 shared Timothy W. GantiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperPharmacology & Toxicology

Emma Quartermain

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 20, 2026

✦ In-depth digest

Chemical augmentation of the validated HepaRGTM CYP induction test method Part 2: Additional laboratory study supported by mRNA analysis

Emma Quartermain, Jinkang Zhang, Tim H. Marczylo…·Miriam Naomi Jacobs

A third laboratory transferred the HepaRG CYP induction assay to six augmentation and four additional non-pharmaceutical chemicals; parallel mRNA data supported enzyme activity calls, with CYP3A4 most concordant.

2 citations

humanbulk RNA-seq

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