Author

Lu Han

Northwestern Polytechnical UniversityORCID 0000-0001-9759-1537Unclaimed ORCID profile · follow to get notified of new preprints

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Lu Han5 papers · Fudan University

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:graph neural network· 1 Assay:Hi-C· 1 Approach:matrix factorization· 1 Organism:mouse· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Jiajie PengiD· 2 shared Jianye HaoiD· 2 shared Jinghao PengiD· 2 shared Tao WangiD· 2 shared Xuequn ShangiD· 2 shared Zhongyu WeiiD· 2 shared Caiwei ZheniD· 1 shared Jingyi LiiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

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10 top collaborators · 41 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Jiajie PengORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintNov 17, 2021

A Deep Learning-based Genome-wide Polygenic Risk Score for Common Diseases Identifies Individuals with Risk

Jiajie Peng, Jingyi Li, Ruijiang Han…·Zhongyu Wei

This paper introduces DeepPRS, a deep learning-based polygenic risk score model that outperforms existing methods in predicting risk for common diseases using genome-wide genotype data.

12 citations

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 30, 2021

A novel framework for single-cell Hi-C clustering based on graph-convolution-based imputation and two-phase-based feature extraction

Caiwei Zhen, Yuxian Wang, Lu Han…·Jiajie Peng

This paper introduces ScHiC-Rep, a framework for single-cell Hi-C clustering that improves imputation and feature extraction, outperforming existing methods on human and mouse datasets.

5 citations

𝕏 PostBluesky