CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway
Daniel Gómez-Cabello, George Pappas, Diana Aguilar Morante, Christoffel Dinant, Jiří Bártek
The paper shows that nascent RNA generated by RNA polymerase II near DNA breaks influences the choice of DNA repair pathway, favoring homologous recombination over non-homologous end joining.
Nature Communications · Sep 9, 2022Peer-reviewedMolecular Biology