Daniel Gómez-Cabello

PERREO: An integrated pipeline for repetitive elements analysis enables the repeatome expression profiling in cancer

PERREO is a pipeline for analyzing repetitive elements in RNA-seq data, showing improved sensitivity for detecting repeat RNA in cancer and other contexts.

RNA Polymerase II-mediated transcription is required for repair of ribosomal DNA breaks in nucleolar caps, guarding against genomic instability

The paper shows RNA polymerase II is essential for repairing rDNA breaks in nucleolar caps, preventing genomic instability and cancer cell death.

CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway

The paper shows that nascent RNA generated by RNA polymerase II near DNA breaks influences the choice of DNA repair pathway, favoring homologous recombination over non-homologous end joining.

RAD51 paralogs regulate double strand break repair pathway choice by limiting Ku complex retention

This study identifies a new role for RAD51 paralogs in regulating double strand break repair pathway choice by limiting Ku complex retention, favoring homology-mediated repair over non-homologous end-joining.