Molecular basis for the host range function of the poxvirus PKR inhibitor E3
Sherry L. Haller, Chorong Park, Ryan C. Bruneau, Dewi Megawati, Chi Zhang, Sameera Vipat, Chen Peng, Tatiana G. Senkevich, G. J. Brennan, Loubna Tazi, Stefan Rothenburg
This paper identifies species-specific interactions between poxvirus PKR inhibitors E3 and K3 and host PKR proteins, challenging the sequestration model for E3 function.
Journal of Virology · Oct 31, 2024Peer-reviewedMicrobiology