Molecular BiologyMolecules and CellsPeer-reviewed
CHD4 conceals aberrant CTCF-binding sites at TAD interiors by regulating chromatin accessibility in mESCs
Sungwook Han, Hosuk Lee, Andrew Lee…·Daeyoup Lee
This study shows that CHD4 regulates chromatin accessibility to hide aberrant CTCF-binding sites within TADs in mESCs, preventing TAD disorganization.