Jason P. DeBruyne

This study finds that the estrous cycle modulates circadian gene expression in the mouse liver, introducing a ~4-day rhythm in 24-hour rhythmicity.

This study shows environmental circadian disruption rewrites liver circadian gene expression rhythms, affecting metabolism, and these changes persist after recovery.

This study identifies a bi-functional N-terminal degradation control sequence in REV-ERBα that regulates its ubiquitination and degradation through interactions with E3 ligases.