Author

Ashleigh B. Irwin

University of Alabama at BirminghamORCID 0000-0001-9840-8837Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna Maria SchreiberiD· 1 shared Farah D. LubiniD· 1 shared Rudhab BahabryiD· 1 shared Silvienne Sint JagoiD· 1 shared Verdion Martina· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperNeuroscience

Anna Maria SchreiberORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintMay 3, 2023

The lncRNA Neat1 is associated with astrocyte reactivity and memory deficits in a mouse model of Alzheimer's disease

Ashleigh B. Irwin, Verdion Martina, Silvienne Sint Jago…·Farah D. Lubin

This study shows that Neat1 overexpression in astrocytes of male AD mice contributes to memory deficits by promoting astrocyte dysfunction, not through neuronal activity changes.

10 citations

mousebulk RNA-seq

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