Author

Silvienne Sint Jago

University of Alabama at BirminghamORCID 0000-0001-7997-8105Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Farah D. LubiniD· 2 shared Rudhab BahabryiD· 2 shared Anna Maria SchreiberiD· 1 shared Ashleigh B. IrwiniD· 1 shared Lara IanoviD· 1 shared Lawrence Ver HoefiD· 1 shared R. Ryley ParrishiD· 1 shared Rebecca M. HauseriD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Farah D. LubinORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 3, 2023

Alterations in DNA 5-hydroxymethylation Patterns in the Hippocampus of an Experimental Model of Refractory Epilepsy

Rudhab Bahabry, Rebecca M. Hauser, Richard G. Sánchez…·Farah D. Lubin

The paper investigates DNA 5-hydroxymethylation (5-hmC) changes in TLE patients and a rat model, finding reduced 5-hmC levels and specific gene associations, with Tet1 manipulation affecting seizure outcomes.

1 citation

humanrat

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NeurosciencebioRxivPreprintMay 3, 2023

The lncRNA Neat1 is associated with astrocyte reactivity and memory deficits in a mouse model of Alzheimer's disease

Ashleigh B. Irwin, Verdion Martina, Silvienne Sint Jago…·Farah D. Lubin

This study shows that Neat1 overexpression in astrocytes of male AD mice contributes to memory deficits by promoting astrocyte dysfunction, not through neuronal activity changes.

10 citations

mousebulk RNA-seq

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