Simon N. Jacob

The paper investigates how prefrontal and thalamic circuits process contextual information during response planning in mice, finding distinct but coordinated representational dynamics.

This study demonstrates that single-neuron recordings from the stroke-lesioned human brain remain stable over 1,240 days, supporting chronic brain-computer interface use after stroke.

This study shows that closed-loop sensory feedback accelerates instrumental learning in mice by reducing trial numbers and improving accuracy during task performance.

The paper tracks prefrontal cortex neurons over time as mice learn and switch rules, finding that activity stabilizes but selectivity remains dynamic.

This study identifies right-hemispheric language networks at single-neuron resolution in a patient with aphasia, showing task-specific encoding and functional organization.

This study identifies mesoscale functional clusters in the primate prefrontal cortex that correlate with individual mnemonic strategies and cognitive control operations.

The paper dissects representational geometry in primate prefrontal cortex into biologically interpretable components linked to single neurons, revealing disentangled memory representations and their neuronal implementation.

This paper describes the use of microelectrode arrays for acute human cortical recordings with single-unit resolution and behavioral monitoring during surgery.