Developmental BiologyThe Journal of Cell BiologyPeer-reviewed
Stage- and tissue-specific gene editing using 4-OHT inducible Cas9 in whole organism
Yaqi Li, Weiying Zhang, Zihang Wei…·Xiaotong Wu
This paper introduces an inducible Cas9 system for tissue- and stage-specific gene editing in zebrafish and mouse embryos, demonstrating its effectiveness in inducing mutations in target genes.