Xiaotong Wu

This study identifies Mif as an oocyte-stored protein that promotes preimplantation embryo development through extracellular signaling, showing its role in blastocyst growth and density-dependent effects.

This study shows that polarity remodeling in zebrafish ventricular cardiomyocyte precursors is essential for ventricular chamber formation and is disrupted in congenital heart defects.

This paper introduces an inducible Cas9 system for tissue- and stage-specific gene editing in zebrafish and mouse embryos, demonstrating its effectiveness in inducing mutations in target genes.

This study shows BMP-Smad1/9 signaling is essential for zebrafish PGC proliferation and survival but not for their fate or migration.

This paper constructs BMSC-macrophage hybrids, evaluates their IgG clearance, immunosuppression, and injury repair capabilities, and finds they effectively modulate immune responses and promote tissue recovery.

The paper shows that global DNA methylation inheritance and enhancer dememorization in zebrafish embryos protect embryonic gene programs by preventing ectopic gene activation.