Author

Matthijs Vynck

Ghent UniversityORCID 0000-0001-9875-385XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:database / resource· 2 Research Focus:software / tool· 2 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1

Frequent Co-Authors

David GleerupiD· 2 shared Jo VandesompeleiD· 2 shared Olivier ThasiD· 2 shared Ward De SpiegelaereiD· 2 shared Abdel Nour Afif· 1 shared Alexandra Bogožalec KoširiD· 1 shared Alexandra S. WhaleiD· 1 shared Alfonso De FalcoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

David GleerupORCID

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3 papers

Recent·Most cited

Robust metabolomics data normalization across scales and experimental designs

Matthijs Vynck, Pablo Vangeenderhuysen, Ellen De Paepe, Tim S. Nawrot, Vera Plekhova, Lynn Vanhaecke

This paper introduces robust normalization methods for metabolomics data to reduce technical variance and improve downstream analysis.

Analytical Chemistry · Jun 11, 2026Peer-reviewedBioinformatics

Introducing the digital PCR data essentials standard to harmonize data structure for clinical and research use

Wim Trypsteen, Matthijs Vynck, Andreas Untergrasser, Alexandra S. Whale, Stefan Rödiger, David Dobnik, Alexandra Bogožalec Košir, Mojca Milavec, Mikael Kubista, Michael Walter Pfaffl, Abdel Nour Afif, Young‐Kyung Bae, Stephen Andrew Bustin, George G. Calin, Chen Yao, , Ward De Spiegelaere

The paper introduces the Digital PCR Data Essentials Standard (DDES) to standardize data structure for dPCR, improving interoperability and reproducibility across platforms and applications.

bioRxiv · Apr 13, 2026 · PreprintBioinformatics

Cross-platform digital PCR evaluation of bovine papilloma virus quantification: introducing PCR-ValiPal for Standardized guided assay validation

David Gleerup, Matthijs Vynck, Lien Gysens, Cindy De Baere, Jo Vandesompele, Olivier Thas, Ann Martens, Maarten Haspeslagh, Ward De Spiegelaere

The paper introduces PCR-ValiPal, a web tool for standardized dPCR assay validation, and evaluates its performance across four platforms for BPV quantification.

bioRxiv · Sep 4, 2025 · PreprintMolecular Biology