Ward De Spiegelaere

LCM-FFPEseq enables high-sensitivity transcriptomics from FFPE tissues with single-cell resolution, detecting over 14,000 genes per sample using as few as 30 cells.

The paper introduces the Digital PCR Data Essentials Standard (DDES) to standardize data structure for dPCR, improving interoperability and reproducibility across platforms and applications.

The paper introduces PCR-ValiPal, a web tool for standardized dPCR assay validation, and evaluates its performance across four platforms for BPV quantification.

The paper identifies a novel fibroblast subtype in the choroid plexus that forms a barrier between the choroid plexus stroma, brain, and cerebrospinal fluid.

This paper introduces three new statistical methods for variance estimation in digital PCR experiments, showing they provide more accurate results than classical binomial methods.