Anne‐Lise Børresen‐Dale

Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of the gene regulatory program in cancers

The paper identifies cis-regulatory mutations in cancer that disrupt gene regulatory programs by affecting both transcriptional and post-transcriptional regulation.

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

The paper identifies breast cancer risk variants associated with tumor subtypes and shows their differential effects on luminal and non-luminal subtypes.

Copy number motifs expose genome instability type and predict driver events and disease outcome in breast cancer

The paper identifies copy number motifs in breast cancer genomes that predict disease outcome and driver events, outperforming existing clinical and genomic markers.

Candidate SNP analyses integrated with mRNA expression and hormone levels reveal influence on mammographic density and breast cancer risk

The paper identifies SNPs associated with mammographic density and breast cancer risk by integrating SNP analyses with mRNA expression and hormone levels.

Haplotypes associated to gene expression in breast cancer: can they lead us to the susceptibility markers?

The paper identifies haplotypes and LD patterns in 80 genes that differ between breast cancer patients and controls, and finds negative correlations in LD patterns for some genes.