Chunyu Geng

This paper investigates how sequencing depth affects low-frequency mutation detection, showing that increasing depth improves fidelity and sensitivity while reducing false positives.

The paper analyzes the genetic diversity of HPV types 16, 18, 52, and 58 in southern China, identifying sublineages and mutations associated with oncogenic potential.

This study evaluates CNV detection performance of DNBSEQ and Illumina platforms using WGS data from NA12878, showing DNBSEQ detects more CNVs with similar sensitivity and precision.

PALM-Seq simultaneously sequences cell-free long and small RNA, identifying pregnancy-related RNAs and sample-specific signatures in plasma, amniotic fluid, leukocytes, and placentas.