Wenjing Wang

This study identifies the CrdRS two-component system as a key regulator of antibiotic-induced biofilm formation in H. pylori through bidirectional control of transporters PlpA and GlnP.

This study develops a sublingual vaccine tablet that induces strong sIgA responses and protects against periodontitis in mice and non-human primates.

This study identifies m6A modifications in PRRSV genome and shows their role in viral replication and host immune response, suggesting potential therapeutic targets.

This study analyzes the humoral immune response to SARS-CoV-2 XBB and JN.1 lineages, showing JN.1 elicits superior neutralization and highlights the need for JN.1-based vaccine boosters.

This study develops ac4C LACE-seq to profile mRNA N4-acetylation in mouse oocytes and shows NAT10 is essential for ac4C modification, which enhances translation efficiency during meiotic maturation.

Deconformer improves cell type deconvolution of cell-free RNA by integrating biological pathways, showing better performance and interpretability across multiple datasets.

The paper demonstrates that TBLCs can efficiently generate blastocyst-like structures with 80% efficiency, outperforming EPSCs in blastoid formation.

This study evaluates how blood storage conditions affect plasma cell-free RNA transcript profiles, finding that mRNA and lncRNA stability is highest at 4°C for 6 hours or RT for 2 hours.

This study compares SARS-CoV-2 viral populations in COVID-19 patients to show narrow transmission bottlenecks and stochastic dynamics in intra-host and inter-host evolution.

This study assesses how temporary storage conditions affect the transcriptome of peripheral blood leukocytes, identifying gene expression changes and stable reference genes.

CNV-PG is a machine-learning framework that improves CNV prediction and genotyping accuracy by reducing false positives and integrating results from multiple callers.

The paper generates and validates an untargeted lipidomics dataset from maternal plasma samples associated with preterm birth, providing a resource for further research.

The paper evaluates five cfDNA isolation kits for plasma, finding that all can isolate cfDNA with varying efficiency, with VZ kit achieving 90% efficiency comparable to QC.

PALM-Seq simultaneously sequences cell-free long and small RNA, identifying pregnancy-related RNAs and sample-specific signatures in plasma, amniotic fluid, leukocytes, and placentas.

This study compares gene expression profiles of leukocytes from different isolation methods, finding that RBC lysis reduces globin mRNA and improves transcriptome quality.