Xinming Liang

Performance evaluation of structural variation detection using DNBSEQ whole-genome sequencing

The paper evaluates SV detection performance across DNBSEQ and Illumina platforms using 40 tools, finding consistent results in metrics and genomic characteristics.

Robust Benchmark Structural Variant Calls of An Asian Using the State-of-Art Long Fragment Sequencing Technologies

The paper establishes high-confidence structural variant calls in an Asian individual using long-read sequencing technologies and validates them through PCR and Sanger sequencing.

Detection and characterization of copy number variants based on whole-genome sequencing by DNBSEQ platforms

This study evaluates CNV detection performance of DNBSEQ and Illumina platforms using WGS data from NA12878, showing DNBSEQ detects more CNVs with similar sensitivity and precision.

An integrated Asian human SNV and indel benchmark combining multiple sequencing methods

The paper constructs a high-confidence Asian variant benchmark using multiple sequencing methods and identifies novel variants in challenging regions.

Advanced Whole Genome Sequencing Using an Entirely PCR-free Massively Parallel Sequencing Workflow

This paper demonstrates that PCR-free whole genome sequencing using the DNBSEQ platform and machine learning variant calling significantly reduces InDel errors and improves variant calling performance.

Reliable Multiplex Sequencing with Rare Index Mis-Assignment on DNB-Based NGS Platform

The paper evaluates index mis-assignment rates on DNB-based sequencing platforms and finds they are exceptionally low, suggesting reliable multiplex sequencing.

Sequencing of Panax notoginseng genome reveals genes involved in disease resistance and ginsenoside biosynthesis

The paper reports the first de novo genome of Panax notoginseng, identifies gene family contractions and expansions related to disease resistance and ABC transporters, and maps key genes in the ginsenoside biosynthesis pathway.