Author

Ke Yu

ORCID 0000-0001-9882-5729Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Russell S. SchwartziD· 1 shared Shuangxia ReniD· 1 shared Xinghua LuiD· 1 shared Yifan XueiD· 1 shared Yifeng TaoiD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperBioinformatics

Russell S. SchwartzORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 11, 2021

De novo Prediction of Cell-Drug Sensitivities Using Deep Learning-based Graph Regularized Matrix Factorization

Shuangxia Ren, Yifeng Tao, Ke Yu…·Xinghua Lu

This paper introduces DeepGRMF, a deep learning model that predicts cell-drug sensitivities by integrating drug structures, signaling impacts, and cell states, outperforming existing methods on cancer datasets.

DOI 10.1101/2021.10.11.462450

humanbulk RNA-seq

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