Author

Christopher Mellor

Cornell UniversityORCID 0000-0001-9902-7040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Carolline Fernanda Rodrigues AscençãoiD· 1 shared Florian HollfelderiD· 1 shared Joel David RogersiD· 1 shared Marcus Bustamante SmolkaiD· 1 shared Meng WangiD· 1 shared Paula E. CoheniD· 1 shared Ralph MinteriD· 1 shared Tegan S. A. HoraniD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Carolline Fernanda Rodrigues AscençãoORCID

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2 papers

Recent·Most cited

The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male mice

Tegan S. A. Horan, Carolline Fernanda Rodrigues Ascenção, Christopher Mellor, Meng Wang, Marcus Bustamante Smolka, Paula E. Cohen

This paper investigates the role of FANCJ in meiotic recombination in mice, finding it involved in early DSB repair and NCO formation but not in MLH1-mediated CO events.

PLoS Genetics · Feb 20, 2024Peer-reviewedGenetics

Gigavalent display of proteins on monodisperse polyacrylamide hydrogels as a versatile modular platform for functional assays and protein engineering

Thomas Fryer, Joel David Rogers, Christopher Mellor, Timo N. Kohler, Ralph Minter, Florian Hollfelder

This paper introduces a modular platform using polyacrylamide hydrogel beads for protein display and functional assays, demonstrating enhanced potency through valency engineering.

ACS Central Science · Aug 1, 2022Peer-reviewedSynthetic Biology