Author

Dengguo Wei

Huazhong Agricultural UniversityORCID 0000-0001-9923-789XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:virus· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Dehua LuoiD· 2 shared Yingxiang Deng· 2 shared Zhiyuan HuangiD· 2 shared Zi WeniD· 2 shared Fan WangiD· 1 shared Ju SuniD· 1 shared Ke PaniD· 1 shared L Y GuoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Dehua LuoORCID

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2 papers

Recent·Most cited

MicrobiologyMolecular Systems BiologyPeer-reviewedJul 30, 2026

RNA Architecture Underlies Discontinuous Transcription and Evolution of Coronavirus

Zi Wen, Lei Chen, Dehua Luo…·Dengguo Wei

This study identifies RNA-RNA interactions and non-canonical sgRNAs in coronaviruses, revealing their role in transcription regulation and immune evasion.

DOI 10.1038/s44320-026-00239-0

virusbulk RNA-seq

𝕏 PostBluesky

GenomicseLifePeer-reviewedJul 2, 2025

Exploiting functional regions in the viral RNA genome as druggable entities

Dehua Luo, Yingge Zheng, Zhiyuan Huang…·Dengguo Wei

The paper applies SHAPE-MaP to identify functional RNA structures in PEDV to guide antiviral drug design.

DOI 10.7554/elife.103923.3

viruslong-read sequencing

𝕏 PostBluesky