BioinformaticsMicrobial GenomicsPeer-reviewed
On the limits of 16S rRNA gene-based metagenome prediction and functional profiling
Monica Steffi Matchado, Malte Christoph Rühlemann, Sandra Reitmeier…·Markus List
This study evaluates 16S rRNA gene-based functional prediction tools using simulated and metagenomic data, finding they lack sensitivity to detect health-related microbiome functional changes.
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