Author

Fabian Frost

Universitätsmedizin GreifswaldORCID 0000-0002-1502-8888Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:GWAS / association mapping· 1 Assay:metagenomics· 1

Frequent Co-Authors

Malte Christoph RühlemanniD· 2 shared Ad MascleeiD· 1 shared Adriaan van der GraafiD· 1 shared Aldons Jake LusisiD· 1 shared Alejandro Arias VásqueziD· 1 shared Alexander KurilshikoviD· 1 shared André FrankeiD· 1 shared André Gerardus UitterlindeniD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Malte Christoph RühlemannORCID

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2 papers

Recent·Most cited

On the limits of 16S rRNA gene-based metagenome prediction and functional profiling

Monica Steffi Matchado, Malte Christoph Rühlemann, Sandra Reitmeier, Tim Kacprowski, Fabian Frost, Dirk Haller, Jan Baumbach, Markus List

This study evaluates 16S rRNA gene-based functional prediction tools using simulated and metagenomic data, finding they lack sensitivity to detect health-related microbiome functional changes.

Microbial Genomics · Feb 29, 2024Peer-reviewedBioinformatics

Large-scale association analyses identify host factors influencing human gut microbiome composition

Alexander Kurilshikov, Carolina Medina‐Gómez, Rodrigo Bacigalupe, Djawad Radjabzadeh, Jun Wang, Ayşe Demirkan, Caroline Ivanne Le Roy, Juan A. Raygoza Garay, Casey T. Finnicum, Xingrong Liu, Daria V. Zhernakova, Marc Jan Bonder, Tue H. Hansen, Fabian Frost, Malte Christoph Rühlemann, , Oluf Borbye Pedersen

The paper identifies 31 host genetic loci influencing gut microbiome composition through GWAS and suggests causal effects in inflammatory diseases.

Nature Genetics · Jan 18, 2021Peer-reviewedGenetics