PhysiologybioRxivPreprint
skNAC is a Key Driver of Cardiomyocyte Integrity Against Pathological Cardiac Hypertrophy and Heart Failure
Laura Guilbert, Justine Dontaine, Natacha Fourny…·Luc Bertrand
This study identifies skNAC as critical for maintaining cardiomyocyte integrity and preventing heart failure by regulating proteome homeostasis and metabolic adaptation during pathological hypertrophy.