Paul Collier

Modulator processes nanopore direct-RNA sequencing data to differentiate transcript-, allele-, and condition-associated RNA modifications, improving the analysis of RNA modifications in single molecules.

This study shows that short-term gonadal cultures of zebra finch PGCs can produce germline chimeras and validated offspring, despite being heterogeneous, unlike long-term chicken PGC cultures.

This study benchmarks two whole-genome sequencing platforms, showing context-specific error rates and highlighting the importance of whole-genome benchmarking for accuracy assessment.

TrueLAMP improves LAMP specificity by inhibiting nonspecific amplification, achieving 100% specificity in no-template controls and a 250 copies/reaction detection limit for SARS-CoV-2.