Author

Kyriaki Savva

Cyprus Institute of Neurology and GeneticsORCID 0000-0002-0001-6593Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:database / resource· 2 Organism:human· 2 Research Focus:software / tool· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

George M. SpyrouiD· 3 shared Marilena M. BourdakouiD· 2 shared Nestoras KarathanasisiD· 2 shared Anastasis OulasiD· 1 shared Efi AthienitiiD· 1 shared George MinadakisiD· 1 shared Grigoris GeorgiouiD· 1 shared Margarita ZachariouiD· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioinformatics

George M. SpyrouORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 4, 2024

Stage-specific gene ratios highlight genes and mechanisms related to presymptomatic and symptomatic Multiple Myeloma

Grigoris Georgiou, George Minadakis, Nestoras Karathanasis…·George M. Spyrou

The paper identifies stage-specific genes and pathways in Multiple Myeloma using monotonic expressed genes (MEGs) and gene pair ratios, showing their potential as biomarkers for disease progression.

DOI 10.1101/2024.11.04.621824

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsInternational Journal of Molecular SciencesPeer-reviewedMay 13, 2024

DReAmocracy: A Method to Capitalize on Prior Drug Discovery Efforts to Highlight Candidate Drugs for Repurposing

Kyriaki Savva, Margarita Zachariou, Marilena M. Bourdakou…·George M. Spyrou

DReAmocracy aggregates drug repurposing data to generate disease suitability scores for candidate drugs, identifying top-ranked drugs for neurodegenerative diseases.

4 citations

statistical modeldrug response / drug discovery

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedApr 18, 2024

Ranking of cell clusters in a single-cell RNA-sequencing analysis framework using prior knowledge

Anastasis Oulas, Kyriaki Savva, Nestoras Karathanasis, George M. Spyrou

The paper introduces a method to rank cell clusters in scRNA-seq using prior knowledge and user input, enhancing biological relevance.

2 citations

humanscRNA-seq

𝕏 PostBluesky