George Minadakis

Multi-omics dissection of Parkinson's patient subgroups associated with motor and cognitive severity

The paper uses multi-omics data to identify molecular factors associated with motor and cognitive severity in Parkinson's disease and stratifies patients into subgroups with distinct severity profiles.

Stage-specific gene ratios highlight genes and mechanisms related to presymptomatic and symptomatic Multiple Myeloma

The paper identifies stage-specific genes and pathways in Multiple Myeloma using monotonic expressed genes (MEGs) and gene pair ratios, showing their potential as biomarkers for disease progression.

Generalized linear models provide a measure of virulence for specific mutations in SARS-CoV-2 strains

This paper uses generalized linear models to identify SARS-CoV-2 mutations associated with changes in viral virulence, highlighting two mutations with opposing effects on deaths and cases per million.

PathWalks: Identifying pathway communities using a disease-related map of integrated information

PathWalks identifies pathway communities using a disease-related map of integrated information, revealing key pathways and potential viral involvement in Alzheimer's and idiopathic pulmonary fibrosis.