Margarita Zachariou

DReAmocracy aggregates drug repurposing data to generate disease suitability scores for candidate drugs, identifying top-ranked drugs for neurodegenerative diseases.

The paper investigates the role of immediate-early genes (IEGs) in genetic networks and identifies MARK4 as a potential therapeutic target for Alzheimer's disease using network analysis and GWAS data.

This paper uses generalized linear models to identify SARS-CoV-2 mutations associated with changes in viral virulence, highlighting two mutations with opposing effects on deaths and cases per million.

This study uses experimentally constrained computational models to analyze how contrast affects gamma rhythm instability in V1, finding that increased input heterogeneity disrupts inhibitory cell pacemaker function.

PathWalks identifies pathway communities using a disease-related map of integrated information, revealing key pathways and potential viral involvement in Alzheimer's and idiopathic pulmonary fibrosis.