BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewed
A combination of systemic mannitol administration and mannitol-modified polyester nanoparticles facilitate gene delivery to the brain through caveolae-mediated endocytosis
Betsy Reshma Gilbert, Chirag Miglani, Arundhati Karmakar…·Munia Ganguli
This paper demonstrates that combining mannitol-modified nanoparticles with systemic mannitol injection enables efficient gene delivery to the brain via caveolae-mediated endocytosis.
2 citations