Genome-Wide Mapping of RNA-Protein Associations via Sequencing
Zhijie Qi, Shuanghong Xue, Junchen Chen…·Sheng Zhong
PRIM-seq maps RNA-protein interactions by generating chimeric DNA sequences, revealing over 350,000 RNA-protein pairs in human cells.
Author
University of California San DiegoORCID 0000-0002-0022-8844Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Zhijie Qi, Shuanghong Xue, Junchen Chen…·Sheng Zhong
PRIM-seq maps RNA-protein interactions by generating chimeric DNA sequences, revealing over 350,000 RNA-protein pairs in human cells.
Kiran Sriram, Zhijie Qi, Dongqiang Yuan…·Zhen Chen
The paper identifies mitochondrial RNAs (mtRNAs) as chromatin-associated RNAs (caRNAs) that regulate nuclear transcription in response to stress and disease.
Riccardo Calandrelli, Xingzhao Wen, John Lalith Charles Richard…·Sheng Zhong
This study investigates how chromatin-associated RNA interacts with 3D genome organization in human cells, revealing a feedback loop between RNA distribution and chromatin structure.