Pharmacology & ToxicologybioRxivPreprint
Multispecies translational evaluation of an NMDA receptor modulator reveals analgesic, autonomic-stabilizing, and stress mitigating effects without evidence of abuse liability
Joanne L. Tuohy, Toshitsugu Ishihara, Sudarshana Govindasamy…·Blaise Mathias Costa
This study evaluates CNS4, an NMDA receptor modulator, across mice, rats, and dogs, showing analgesic, autonomic-stabilizing, and stress-reducing effects without abuse liability.