Cancer BiologybioRxivPreprint
NF-κB mediates transactivation of HNRNPD, resulting in PTEN destabilization and constitutive activation of the PI3K-AKT pathway in oral cancer cells
Vikas Kumar, Anjani Mittal, Anurag Kumar…·Shyam Singh Chauhan
This study shows hnRNPD, upregulated by NF-κB, destabilizes PTEN mRNA, activates PI3K-AKT pathway, and promotes oral cancer cell proliferation, migration, and survival.
DOI 10.1101/2025.01.05.631360