Author

Mandy Muller

Centre Hospitalier Universitaire VaudoisORCID 0000-0002-0056-3589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jacob MilesiD· 2 shared Samantha Schultz· 2 shared Will Dwyer· 2 shared Britt A. GlaunsingeriD· 1 shared Daniel Macveigh-FierroiD· 1 shared Yahaira BermudeziD· 1 shared

Activity by Year

2017-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

Jacob MilesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Virally encoded interleukin-6 (vIL-6) coordinates with human IL-6 to modulate cytokine expression during KSHV infection

Yahaira Bermudez, Samantha Schultz, Jacob Miles, Will Dwyer, Mandy Muller

This study shows that viral IL-6 (vIL-6) and human IL-6 work together to influence cytokine expression and immune responses during KSHV infection.

bioRxiv · Oct 2, 2025 · PreprintMicrobiology

IL-6 Evades KSHV-Mediated Hyperadenylation repression via CRM1-Dependent Nuclear Export.

Samantha Schultz, Jacob Miles, Will Dwyer, Daniel Macveigh-Fierro, Mandy Muller

The paper shows that IL-6 mRNA escapes KSHV-induced nuclear retention via CRM1-dependent export, bypassing SOX-mediated decay and maintaining cytoplasmic stability.

bioRxiv · Jun 5, 2025 · PreprintMicrobiology

Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases

Mandy Muller, Britt A. Glaunsinger

The paper identifies RNA elements that protect mRNAs from viral endonuclease cleavage, showing they are specific to viral enzymes and not cellular ones.

PLoS Pathogens · Aug 25, 2017Peer-reviewedMolecular Biology