Clinical Impact of Pharmacogenetic Risk Variants in a Large Chinese Cohort
Chun-Yu Wei, Ming‐Shien Wen, Chih-Kuang Cheng, Yi‐Jing Sheen, Tsung‐Chieh Yao, Sing-Lian Lee, Jer-Yuarn Wu, Ming-Fang Tsai, Ling-Hui Li, Chun‐Houh Chen, Cathy S.-J. Fann, Hsin‐Chou Yang, Yen‐Tsung Huang, Hung-Hsin Chen, Yi-Min Liu, , Chien‐Ming Lin
The paper evaluates the clinical impact of pharmacogenetic risk variants in a large Han Chinese cohort, finding that while most carry risk variants, the excess risk of adverse events is small and most patients do not experience adverse outcomes.
Nature Communications · Jul 9, 2025Peer-reviewedGenetic & Genomic Medicine