Tugrul Doruk

High-throughput, single-cell-encoded colony imaging reveals infection-linked heterogeneity

HeteroTyper quantifies phenotypic heterogeneity in bacterial colonies across multiple media types, revealing tissue-specific differences and growth dynamics during infection.

Sample-derived cDNA guides broad host RNA depletion for in vivo pathogen transcriptomics

This paper introduces a method to deplete host RNA from infected tissues, enabling efficient detection of bacterial transcripts in vivo with reduced sequencing depth.