Author

David J. Bernard

National Institutes of HealthORCID 0000-0002-0057-9353Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:mouse· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne Parle‐McDermottiD· 2 shared Darren J WalshiD· 2 shared Denise H. HaroldiD· 2 shared Faith PangilinaniD· 2 shared Lawrence C. BrodyiD· 2 shared Madison L. EspositoiD· 2 shared Joanna L. FiddleriD· 1 shared Martha S. FieldiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersMolecular Biology

Anne Parle‐McDermottORCID

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2 papers

Recent·Most cited

Vitamin B12 status and folic acid supplementation influence mitochondrial heteroplasmy levels in mice as they age.

Darren J Walsh, David J. Bernard, Joanna L. Fiddler, Faith Pangilinan, Madison L. Esposito, Denise H. Harold, Martha S. Field, Anne Parle‐McDermott, Lawrence C. Brody

The paper investigates how vitamin B12 and folic acid affect mitochondrial DNA heteroplasmy in mice and suggests potential sex-specific effects in humans.

PNAS Nexus · Mar 15, 2024Peer-reviewedMolecular Biology

Mito-SiPE: A sequence-independent, PCR-free mitochondrial DNA enrichment method for ultra-deep sequencing that minimises amplification and alignment artifacts.

Darren J Walsh, David J. Bernard, Faith Pangilinan, Madison L. Esposito, Denise H. Harold, Anne Parle‐McDermott, Lawrence C. Brody

The paper introduces Mito-SiPE, a PCR-free mitochondrial DNA enrichment method that reduces amplification and alignment artifacts, enabling ultra-deep sequencing of mtDNA in mouse tissues.

Communications Biology · Nov 19, 2022Peer-reviewedGenomics