Author

Leon Hubbard

Cardiff UniversityORCID 0000-0002-0064-6755Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Leon Hubbard1 paper

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 3 Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 6 Approach:statistical model· 5 Research Focus:GWAS / association mapping· 3 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Assay:GWAS summary statistics· 2 Approach:Bayesian inference· 1 Approach:benchmark study· 1

Frequent Co-Authors

Nigel M. WilliamsiD· 6 shared Catherine BresneriD· 4 shared Donald G. GrossetiD· 4 shared John HardyiD· 4 shared Michael LawtoniD· 4 shared Regina Hertfelder ReynoldsiD· 4 shared Yoav Ben‐ShlomoiD· 4 shared Huw R. MorrisiD· 3 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

6 shared papersNeuroscience

Nigel M. WilliamsORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Neurosciencenpj Parkinson s DiseasePeer-reviewedMar 2, 2025

Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson's disease: A DNA co-methylation network analysis

Joshua Harvey, Adam R. Smith, Luke Stephen Weymouth…·Katie Lunnon

The paper identifies a DNA methylation module in the substantia nigra associated with depressive symptoms in Parkinson's disease.

8 citations

humanDNA methylation

𝕏 PostBluesky

Genetic & Genomic Medicinenpj Parkinson s DiseasePeer-reviewedJun 7, 2024

Genome-wide determinants of mortality and motor progression in Parkinson's disease

Manuela M. X. Tan, Michael Lawton, Miriam I. Pollard…·Huw R. Morris

This study identifies six novel genetic loci associated with Parkinson's disease mortality and motor progression using genome-wide survival analysis.

17 citationstop 5%

humanwhole-exome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicineBrainPeer-reviewedNov 7, 2022

Association between the LRP1B and APOE loci and the development of Parkinson's disease dementia

Raquel Real, Alejandro Martínez-Carrasco, Regina Hertfelder Reynolds…·Huw R. Morris

This study identifies APOE-ε4 and LRP1B as genetic risk factors for Parkinson's disease dementia using genome-wide survival analysis in 3,964 PD cases.

61 citations

humanstatistical model

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 18, 2021

Universal latent axes capturing Parkinson's patient deep phenotypic variation reveals patients with a high genetic risk for Alzheimer's disease are more likely to develop a more aggressive form of Parkinson's.

Cynthia Sandor, Stephanie Millin, Andrew Dahl…·Caleb Webber

1 citation

humanelectronic health records

𝕏 PostBluesky

Genetic & Genomic MedicineMovement DisordersPeer-reviewedOct 28, 2020

Genome-wide association studies of cognitive and motor progression in Parkinson's disease

Manuela M. X. Tan, Michael Lawton, Edwin Jabbari…·Huw R. Morris

This paper identifies genetic variants associated with cognitive and motor progression in Parkinson's disease using GWAS and longitudinal cohort data.

161 citations

humanGWAS summary statistics

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 5, 2019

Integration of eQTL and Parkinson’s disease GWAS data implicates 11 disease genes

Demis A. Kia, David Zhang, Sebastian Guelfi…·Nicholas William Wood

This paper integrates eQTL and Parkinson’s disease GWAS data to identify 11 disease genes and pathways involved in PD risk through colocalisation, TWAS, and network analysis.

11 citations

humanGWAS summary statistics

𝕏 PostBluesky