Author

Rafael Bravo

Moffitt Cancer CenterORCID 0000-0002-0065-4341Unclaimed ORCID profile · follow to get notified of new preprints

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Rafael Bravo2 papers

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Approach:machine learning (classical)· 1 Approach:matrix factorization· 1

Frequent Co-Authors

Alexander R.A. AndersoniD· 1 shared Amer A. BegiD· 1 shared Bahar TercaniD· 1 shared Boris H. AguilariD· 1 shared David A. HormuthiD· 1 shared Ernesto A. B. F. LimaiD· 1 shared Jhanelle E. GrayiD· 1 shared Mark Robertson‐TessiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alexander R.A. AndersonORCID

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2 papers

Recent·Most cited

Estimating glioblastoma migration-to-proliferation ratio from single time-point MRI data via radial density distribution

Rafael Bravo, David A. Hormuth, Ernesto A. B. F. Lima, Bahar Tercan, Boris H. Aguilar, Thomas E. Yankeelov

A reaction-diffusion model fitted to shell-averaged tumor density from one pre-treatment MRI estimates glioblastoma migration/proliferation ratio (D/k); in BraTS 2017, higher D/k went with shorter overall survival.

bioRxiv · Oct 31, 2026 · PreprintSystems Biology✦ In-depth digest

The impact of normal tissue density on tumor growth and evolution in a 3D whole-tumor model of lung cancer

Rafael Bravo, Mark Robertson‐Tessi, Scott Joseph Antonia, Jhanelle E. Gray, Amer A. Beg, Robert A. Gatenby, Matthew B. Schabath, Alexander R.A. Anderson

This study uses a 3D computational model to show that tumor growth rates depend on tissue density and metabolic strategies like glycolysis or angiogenesis in lung cancer.

bioRxiv · Sep 25, 2025 · PreprintCancer Biology