Author

Ernesto A. B. F. Lima

Texas Advanced Computing CenterORCID 0000-0002-9219-8784Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ernesto A. B. F. Lima1 paper

Biology Disciplines

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Systems Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:matrix factorization· 1

Frequent Co-Authors

Thomas E. YankeeloviD· 3 shared Angela M. JarrettiD· 1 shared Anna G. SoraceiD· 1 shared Bahar TercaniD· 1 shared Boris H. AguilariD· 1 shared Caleb M. PhillipsiD· 1 shared David A. HormuthiD· 1 shared Hoon ChoiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersSystems Biology

Thomas E. YankeelovORCID

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3 papers

Recent·Most cited

Estimating glioblastoma migration-to-proliferation ratio from single time-point MRI data via radial density distribution

Rafael Bravo, David A. Hormuth, Ernesto A. B. F. Lima, Bahar Tercan, Boris H. Aguilar, Thomas E. Yankeelov

A reaction-diffusion model fitted to shell-averaged tumor density from one pre-treatment MRI estimates glioblastoma migration/proliferation ratio (D/k); in BraTS 2017, higher D/k went with shorter overall survival.

bioRxiv · Oct 31, 2026 · PreprintSystems Biology✦ In-depth digest

Modeling tumor dynamics and predicting response to chemo-, targeted-, and immune-therapies in a murine model of pancreatic cancer

Krithik Vishwanath, Hoon Choi, Mamta Gupta, Rong Zhou, Anna G. Sorace, Thomas E. Yankeelov, Ernesto A. B. F. Lima

The paper develops a mathematical model to predict pancreatic cancer response to various therapies in mice, showing high accuracy in fitting and predicting tumor dynamics.

bioRxiv · Jan 3, 2025 · PreprintBioinformatics

Towards integration of time-resolved confocal microscopy of a 3D in vitro microfluidic platform with a hybrid multiscale model of tumor angiogenesis

Caleb M. Phillips, Ernesto A. B. F. Lima, Manasa Gadde, Angela M. Jarrett, Marissa Nichole Rylander, Thomas E. Yankeelov

This study calibrates a multiscale tumor angiogenesis model with time-resolved microscopy data to predict vascular sprouting and assess model accuracy.

PLoS Computational Biology · Jan 18, 2023Peer-reviewedSystems Biology