Bahar Tercan

Estimating glioblastoma migration-to-proliferation ratio from single time-point MRI data via radial density distribution

A reaction-diffusion model fitted to shell-averaged tumor density from one pre-treatment MRI estimates glioblastoma migration/proliferation ratio (D/k); in BraTS 2017, higher D/k went with shorter overall survival.

Cellular heterogeneity and therapeutic response profiling of human IDH+ glioma stem cell cultures

This paper characterizes IDH+ glioma stem cell cultures to model GBM biology and therapeutic response, showing reproducible survival curves and methods to track cellular heterogeneity.

Predicting microsatellite instability from whole slide images using texture features

This study predicts microsatellite instability from whole slide images using texture features, achieving high AUC scores on both tile and sample levels.

spongEffects: ceRNA modules offer patient-specific insights into the miRNA regulatory landscape

spongEffects identifies patient-specific ceRNA modules to provide insights into miRNA regulatory activity using gene expression data alone.

SL-Cloud: A Computational Resource to Support Synthetic Lethal Interaction Discovery

SL-Cloud is a cloud-based resource that facilitates the prediction and comparison of context-specific synthetic lethal interactions using multi-omic datasets.