BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Enzymatic carbon-fluorine bond cleavage by human gut microbes
Silke I. Probst, Florian D. Felder, Victoria Poltorak…·Serina L. Robinson
This paper discovers that human gut microbes can cleave carbon-fluorine bonds using defluorinases, identifies structural features predictive of this activity, and develops a screening assay for detecting such enzymes.
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