Ritesh Mewalal

Sorghum Metabolic Atlas: Large-Scale Subcellular Localization Resource for Sorghum Metabolic Enzymes

The paper experimentally determines subcellular localization of 234 metabolic enzymes in sorghum, providing a resource for metabolic organization studies.

TOR inhibition drives accumulation of amino acids through transcriptional activation in algae

This study shows that TOR inhibition in algae increases amino acid levels through transcriptional activation of biosynthesis pathways and identifies a conserved transcription factor involved in nitrogen metabolism.

Enzymatic carbon-fluorine bond cleavage by human gut microbes

This paper discovers that human gut microbes can cleave carbon-fluorine bonds using defluorinases, identifies structural features predictive of this activity, and develops a screening assay for detecting such enzymes.

Functional genomic screening in Komagataella phaffii enabled by high-activity CRISPR-Cas9 library

The paper develops a high-activity CRISPR-Cas9 library for Komagataella phaffii and uses it to identify essential genes related to protein production, secretion, and glycosylation.