Jeehyun Kwag

Egocentric spatial scaffolds organize cortical memory engrams

The paper identifies a scaffold-engram architecture in the retrosplenial cortex that reconstructs episodic memories by reinstating self-referenced spatial representations.

Retrosplenial PV and SST interneurons shape egocentric spatial precision and stability

This study identifies distinct roles of PV and SST interneurons in balancing egocentric spatial coding precision and stability during navigation.

Memory encoding and retrieval by retrosplenial parvalbumin interneurons is impaired in Alzheimer's disease model mice

This study shows that dysfunction in retrosplenial parvalbumin interneurons impairs contextual fear memory retrieval in Alzheimer's disease model mice.

Egocentric vector coding of geometric vertex in the retrosplenial cortex

The paper identifies vertex cells in the granular retrosplenial cortex that encode egocentric vertex information, contributing to geometric cognitive maps for navigation.

Retrosplenial cortex is necessary for spatial and non-spatial latent learning in mice

This study shows that the retrosplenial cortex is necessary for both spatial and non-spatial latent learning in mice, specifically during the preconditioning phase.

In vivo direct imaging of neuronal activity at high temporo-spatial resolution

This paper introduces DIANA-fMRI, a method for high-temporal and spatial resolution imaging of neuronal activity in vivo, demonstrating its ability to capture spiking activity and propagation in mice brains.

Distinct roles of parvalbumin and somatostatin interneurons in the synchronization of spike-times in the neocortex

The paper investigates the role of parvalbumin and somatostatin interneurons in spike-time synchronization in the neocortex, finding frequency-specific contributions to spatio-temporal synchronization.

Optogenetic activation of SST-positive interneurons restores hippocampal theta oscillation impairment induced by soluble amyloid beta oligomers in vivo

This study shows that optogenetic activation of SST+ interneurons restores theta oscillation impairment caused by AβO in vivo.

Neocortical inhibitory interneuron subtypes display distinct responses to synchrony and rate of inputs

The paper investigates how different inhibitory interneuron subtypes in the neocortex respond to information encoded in spike synchrony versus rate.